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Ken PopeSubject: Multivitamins Reduce Breast Cancer Risk 30% The American Association for Cancer Research issued the following newsrelease: Vitamins and calcium supplements appear to reduce the risk of breastcancer, according to findings presented at the American Association forCancer Research 101st Annual Meeting 2010. “It is not an immediate effect. You don’t take a vitamin today and yourbreast cancer risk is reduced tomorrow,” said Jaime Matta, Ph.D.,professor in the Ponce School of Medicine in Puerto Rico. “However, we did see a long-term effect in terms of breast cancer reduction.” Matta said the findings suggest that the calcium supplements are actingto enhance DNA repair capacity, a complex biological process involvingmore than 200 proteins that, if disrupted, can lead to cancer. “This process involves at least five separate pathways and is criticalfor maintaining genomic stability,” said Matta. “When the DNA is not repaired, it leads to mutation that leads to cancer.” The study included 268 women with breast cancer and 457 healthycontrols. Women were more likely to have breast cancer if they wereolder, had a family history of breast cancer, had no history ofbreastfeeding and had lower DNA repair capacity. Vitamin supplements appeared to reduce the risk of breast cancer byabout 30 percent. Calcium supplements reduced the risk of breast cancer by 40 percent. After controlling for the level of DNA repair capacity, calciumsupplements were no longer as protective, but the link between vitaminsupplements and breast cancer reduction remained. “We’re not talking about mega doses of these vitamins and calciumsupplements, so this is definitely one way to reduce risk,” said Matta. Ken Pope

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